NDSB-211蛋白结晶试剂盒Hampton Research

Hampton Research蛋白结晶试剂盒

NDSB-211
NDSB-211

NDSB-211

NDSB-211

NDSB-211

NDSB-211

Products > Optimize Reagents > Optimize – Solubilizing Agents (NDSB) > NDSB-211

NDSB-211

Applications

  • Crystallization grade NDSB-211 for formulating screens or for optimization

Features

  • Efficiently solubilizes proteins at non-denaturing concentrations
  • Useful in preventing protein aggregation
  • Non detergent sulfobetaines (NDSB) are used for protein folding, renaturation and crystallization
  • Protein specific additive for solubility and stability

Description

The NDSB are a group of zwitterionic compounds that can reduce aggregation and aid in refolding proteins found in inclusion bodies and bacterial expression systems.

Non detergent sulfobetaines have a sulfobetaine hydrophilic group and a short hydrophobic group that cannot aggregate to form micelles, therefore NDSB’s are not considered detergents. NDSB increase the extraction yield (up to 30%) of membrane, nuclear and cyto-skeletal associated proteins. The short hydrophobic groups combined with the charge neutralization of the sulfobetaine group results in higher yields of membrane proteins. NDSB have been used in refolding and renaturation of chemically and thermally denatured proteins.

Typical useful NDSB concentration in protein sample is 0.5-1.0 M.

NDSB-211
Synonyms: Dimethyl(2-hydroxyethyl)ammonium propane sulfonate or Non detergent sulfobetaine 211
C7H17NO4S
Mr 211.30
Purity: ≥99%
Hygroscopic
Store at room temperature (+20 degrees Celsius)

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NDSB-211

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NDSB-211

NDSB-211

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NDSB-211

CAT NO

HR2-793

NAME

NDSB-211

DESCRIPTION

5 grams

PRICE

$127.00

cart quote

Support Material(s)

NDSB-211 HR2-793 NDSB-211 User GuideNDSB-211 HR2-793 NDSB-211 SDS

Certificate Of Analysis

References

1. Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.

2. Vuillard, L., et al. 1995. Biochem. J. 305-, 337.

NDSB-211 NDSB-211

Hampton Research, first in crystallization since 1991, developing and delivering crystallization and optimization screens, reagents, plates, and other tools for the crystallization of biological macromolecules, including proteins (antibody), peptides (insulin), and nucleic acids (DNA).

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